2025
50. Yuqing Shen, Bo Lu, Biao Ma, Xiong Ding*. Enhanced One-Pot Dual-CRISPR-Based Assay Lyophilized on a 3D-Printed Disc for Field-Deployable Multiplex Bacteria Detection. Advanced Science, 2025, e09355. https://doi.org/10.1002/advs.202509355
49. Jingjing Sun, Weihong Yin, Dan Shen, Bingnan Wang, Jiaole Fang, Xiong Ding, Ying Mu*. ERotary Cylinder Based Fully Integrated Microfluidic System for the Multiplex Molecular Diagnosis of Respiratory Pathogens. Sensors and Actuators B: Chemical, 2025, 138820. https://doi.org/10.1016/j.snb.2025.138820
48. Yi Xie, Yi Li, Xiong Ding*, Meilin Weng*, Kun Yin*. Heparin’s Inhibition Capability on DNA Polymerase Enables Probe-Free Heparin Quantification. Research Square, 2025, Preprint. https://doi.org/10.21203/rs.3.rs-7559255/v1
2024
47. Yi Xie, Kai Jiang, Yuqian Zhang, Liqin Cao, Xiaokui Guo, Jun Shi*, Xiong Ding*, Kun Yin*. Enhanced Two-Step LAMP-CRISPR Assay with an Engineered Zst Polymerase for Contamination-Free and Ultrasensitive DNA Detection. Analytical Chemistry, 2024, 96, 38, 15493–15502. https://doi.org/10.1021/acs.analchem.4c03965
46. Xiong Ding*#, Yaru Wang#, Yuxin Gui, Chuankun Yang. Two-Stage Mixed-Dye-Based Isothermal Amplification with Ribonuclease-Cleavable Enhanced Probes for Dual-Visualization Detection of SARS-CoV-2 Variants of Interest. Advanced Science, 2024, 2401988, https://doi.org/10.1002/advs.202401988
45. Youfa Wang#, Jin Wang*#, Rui Wang, Yang Liu, Geoffrey IN Waterhouse*, Xiong Ding*, Vijaya Raghavan. Single aptamer hairpin DNA-based response system combined with COF-based signal amplification strategy for ultrasensitive detection of cancer-associated thrombin. Chemical Engineering Journal, 2024, 151224, https://doi.org/10.1016/j.cej.2024.151224
44. Yakun Gao, Gangsheng Chen, Biao Ma, Yaru Wang, Yanjie Wei, Yunzhi Qian, Ziyan Kong, Yian Hu, Xiong Ding, Zhi Ping, Chao Zhao, Hong Liu. Phase Transition-Driven Encapsulation of Biomolecules Using Liquid Metal with On-Demand Release for Biomedical Applications. Biosensors and Bioelectronics, 2024, 116403, https://doi.org/10.1016/j.bios.2024.116403
2023
43. Yaru Wang, Lanxiang Zhang, Yuqing Shen, Evan Yi-Wen Yu, and Xiong Ding*. Nested Phosphorothioated Hybrid Primer-Mediated Isothermal Amplification for Specific and Dye-Based Subattomolar Nucleic Acid Detection at Low Temperatures. ACS Sensors, 2023, https://doi.org/10.1021/acssensors.2c02754
42. Ziyue Li, Naoki Uno, Xiong Ding, Lori Avery, David Banach, and Changchun Liu. Bioinspired CRISPR-Mediated Cascade Reaction Biosensor for Molecular Detection of HIV Using a Glucose Meter, ACS Nano, 2023, https://pubs.acs.org/doi/10.1021/acsnano.2c12754
41. Jingwen Mo, Shichang Wang, Jiaying Zeng, Xiong Ding. Aptamer-based Upconversion Fluorescence Sensor for Doxorubicin Detection. Journal of Fluorescence. 2023, 33(5):1897-1905. https://doi.org/10.1007/s10895-023-03184-5
2022
40. Ziyue Li, Xiong Ding, Kun Yin, Lori Avery, Enrique Ballesteros, Changchun Liu. Instrument-free, CRISPR-based diagnostics of SARS-CoV-2 using self-contained microfluidic system. Biosensors and Bioelectronics, 2022, 199, 113865. https://doi.org/10.1016/j.bios.2021.113865
2021
39. Xiong Ding, Ziyue Li, Lori Avery, Enrique Ballesteros, Rohit Makol, and Changchun Liu, pH-EVD: A pH Paper-based Extraction and Visual Detection System for Instrument-free SARS-CoV-2 Diagnostics, Advanced NanoBiomed Research, 2021. https://doi.org/10.1002/anbr.202100101 (Non-SCI)
38. Xiong Ding, Ziyue Li, Changchun Liu. Monolithic, 3D-Printed Lab-on-Disc Platform for Multiplexed Molecular Detection of SARS-CoV-2. Sensors and Actuators B: Chemical. 2021, 351:130998. https://doi.org/10.1016/j.snb.2021.130998
37. Ziyue Li, Xiong Ding, Kun Yin, Zhiheng Xu, Kumarasen Cooper, Changchun Liu. Electric field enhanced electrochemical CRISPR biosensor for DNA detection. Biosensors and Bioelectronics, 2021,192:113498. doi: 10.1016/j.bios.2021.113498
36. Zhiheng Xu, Xiong Ding, Kun Yin, Z Li, JA Smyth, MB Sims, HA McGinnis, Changchun Liu. TickPhone App: A Smartphone Application for Rapid Tick Identification Using Deep Learning. Applied Sciences. 2021, 11 (16), 7355
35. Kun Yin, Xiong Ding, Ziyue Li, Maroun M Sfeir, Enrique Ballesteros, Changchun Liu. Autonomous Lab-on-Paper for Multiplexed, CRISPR-based Diagnostics of SARS-CoV-2. Lab on a Chip. 2021, 6. https://doi.org/10.1039/D1LC00293G
34. Kun Yin, Xiong Ding, Zhiheng Xu, Ziyue Li, Xingyu Wang, Hui Zhao, Clifford Otis, Baikun Li, Changchun Liu. Multiplexed colorimetric detection of SARS-CoV-2 and other pathogens in wastewater on a 3D printed integrated microfluidic chip. Sensors and Actuators B: Chemical. 2021,130242. https://doi.org/10.1016/j.snb.2021.130242
33. Zhiheng Xu, Kun Yin, Xiong Ding, Ziyue Li, Xuanhao Sun, Baikun Li, Rajesh V Lalla, Robert Gross, Changchun Liu. An integrated E-Tube cap for sample preparation, isothermal amplification and label-free electrochemical detection of DNA. Biosensors and Bioelectronics, 2021, 113306. https://doi.org/10.1016/j.bios.2021.113306
32. Xiong Ding, Kun Yin, Ziyue Li, Maroun M. Sfeir, Changchun Liu. Sensitive quantitative detection of SARS-CoV-2 in clinical samples using digital warm-start CRISPR assay. Biosensors and Bioelectronics, 2021, 113218. https://doi.org/10.1016/j.bios.2021.113218
2020
31. Xiong Ding, Kun Yin, Ziyue Li, Rajesh V. Lalla, Enrique Ballesteros, Maroun M. Sfeir, Changchun Liu. Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay. Nature Communications, 2020, 11. https://doi.org/10.1038/s41467-020-18575-6
30. Xiong Ding, Kun Yin, Ziyue Li, Vikram Pandian, Joan A Smyth, Zeinab Helal, Changchun Liu. Cleavable hairpin beacon-enhanced fluorescence detection of nucleic acid isothermal amplification and smartphone-based readout. Scientific Reports, 2020, 10. https://doi.org/10.1038/s41598-020-75795-y
29. Wenshuai Wu, Fengtian Wu, Shan Zhang, Xiong Ding, Tao Zhang, Ying Yang, Ying Mu. A self-powered bidirectional partition microfluidic chip with embedded microwells for highly sensitive detection of EGFR mutations in plasma of non-small cell lung cancer patients. Talanta, 2020, 220, 121426.
28. Kun Yin, Xiong Ding, Ziyue Li, Hui Zhao, Kumarasen Cooper, Changchun Liu*: Dynamic aqueous multiphase reaction system for one-pot CRISPR-Cas12a based ultrasensitive and quantitative molecular diagnosis. Analytical Chemistry, 2020, 92, 8561-8568.
2019
27. Xiong Ding, Kun Yin, Ju Chen, Kepeng Wang, Changchun Liu*: Ribonuclease-dependent cleavable beacon primer triggering DNA amplification for single nucleotide mutation detection with ultrahigh sensitivity and selectivity. Chemical Communications, 2019, 55, 12623-12626.
26. Xiong Ding, Zhiheng Xu, Kun Yin, Maroun Sfeir, Changchun Liu*: Dual-Priming Isothermal Amplification (DAMP) for Highly Sensitive and Specific Molecular Detection with Ultralow Nonspecific Signals. Analytical chemistry, 2019, 91, 12852-12858.
25. Xiong Ding, Guoping Wang, Ying Mu*: Single enzyme-based stem-loop and linear primers co-mediated exponential amplification of short gene sequences. Analytica Chimica Acta, 2019, 1081, 193-199.
24. Jingjing Sun, Jiumei Hu, Tong Gou, Xiong Ding, Qi Song, Wenshuai Wu, Guoping Wang, Juxin Yin, Ying Mu*: Power-free polydimethylsiloxane femtoliter-sized arrays for bead-based digital immunoassays. Biosensors and Bioelectronics, 2019, 139, 111339.
23. Shufang Zhou, Tong Gou, Jiumei Hu, Wenshuai Wu, Xiong Ding, Weibo Fang, Zhenming Hu, Ying Mu*: A highly integrated real-time digital PCR device for accurate DNA quantitative analysis. Biosensors and Bioelectronics, 2019, 128, 151-158.
22. Xiong Ding, Kevin D. Clark, Marcelino Varona, Miranda N. Emaus, Jared L. Anderson*: Magnetic ionic liquid-enhanced isothermal nucleic acid amplification and its application to rapid visual DNA analysis. Analytica Chimica Acta, 2019, 1045, 132-140.
2018
21. Xiong Ding, Michael G. Mauk, Kun Yin, Karteek Kadimisetty, Changchun Liu*: Interfacing Pathogen Detection with Smartphones for Point-of-Care Applications (Review). Analytical Chemistry, 2018, 91, 655−672.
20. Tong Gou, Jiumei Hu, Wenshuai Wu, Xiong Ding, Shufang Zhou, Weibo Fang, Ying Mu*: Smartphone-based mobile digital PCR device for DNA quantitative analysis with high accuracy. Biosensors and Bioelectronics, 2018, 120, 144-152.
19. Wenshuai Wu, Shufang Zhou, Jiumei Hu, Guoping Wang, Xiong Ding, Tong Gou, Jingjing Sun, Tao Zhang, Ying Mu*: A Thermosetting Oil for Droplet-Based Real-Time Monitoring of Digital PCR and Cell Culture. Advanced Functional Materials, 2018, 28, 1803559.
18. Bo Pang, Kaiyue Fu, Yushen Liu, Xiong Ding, Jiumei Hu, Wenshuai Wu, Kun Xu, Song Xiuling, Juan Wang, Ying Mu*, Chao Zhao*, Juan Li*: Development of a self-priming PDMS/paper hybrid microfluidic chip using mixed-dye-loaded loop-mediated isothermal amplification assay for multiplex foodborne pathogens detection. Analytica Chimica Acta, 2018, 1040, 81-89.
17. Marcelino Varona, Xiong Ding, Kevin D Clark, Jared L Anderson*: Rapid Solid-Phase Microextraction of DNA from Mycobacteria in Artificial Sputum Samples Enables Visual Detection using Isothermal Amplification. Analytical Chemistry, 2018, 90, 6922-6928.
16. Yuwei Cui, Ying Mu, Li Ma, Xiong Ding, Zongyu Fang, Yan Wang, Qingqing Wu*: [Detection Method of Human Papillomavirus HPV16 and HPV52 by Dual Fluorescence Isothermal Multiple-Self-Matching-Initiated Amplification] (Article in Chinese). Journal of Jilin University (Science Edition), 2018, 56, 1017-1023. (Non-SCI)
15. Wanghua Wu, Tao Zhang*, Da Han, Hongliang Fan, Guizhi Zhu, Xiong Ding, Cuichen Wu, Mingxu You, Liping Qiu, Juan Li, Liqin Zhang, Xiang Lian, Rong Hu, Ying Mu, Jianguang Zhou, Weihong Tan*: Aligner-mediated cleavage of nucleic acids and its application to isothermal exponential amplification. Chemical Science, 2018, 9, 3050-3055.
14. Xitian Peng, Kevin D Clark, Xiong Ding, Chenghui Zhu, Marcelino Varona, Miranda N Emaus, Jiwoo An, Jared L Anderson*: Coupling oligonucleotides possessing a poly-cytosine tag with magnetic ionic liquids for sequence-specific DNA analysis. Chemical Communications, 2018, 54, 10284-10287.
2017
13. Bo Pang#, Xiong Ding#, Guoping Wang, Chao Zhao, Yanan Xu, Kaiyue Fu, Jingjing Sun, Xiuling Song, Wenshuai Wu, Yushen Liu, Qi Song, Jiumei Hu, Juan Li, Ying Mu*: Rapid and quantitative detection of Vibrio parahemolyticus by the mixed-dye-based loop-mediated isothermal amplification assay on a self-priming compartmentalization microfluidic chip. Journal of Agricultural and Food Chemistry, 2017, 65, 11312-11319.
12. Guoping Wang#, Xiong Ding#, Jiumei Hu, Wenshuai Wu, Jingjing Sun, Ying Mu*: Unusual isothermal multimerization and amplification by the strand-displacing DNA polymerases with reverse transcription activities. Scientific Reports, 2017, 7, 13928.
11. Wenshuai Wu, Xiong Ding, Ying Mu*: [A picoliter microfluidic chip driven by negative pressure for quantifying nucleic acid accurately with isothermal amplification] (Article in Chinese). Chinese Journal of Chromatography, 2017, 35, 351-356. (Non-SCI)
2016
10. Xiong Ding, Guoping Wang, Jingjing Sun, Tao Zhang, Ying Mu*: Fluorogenic bidirectional displacement probe-based real-time isothermal DNA amplification and specific visual detection of products. Chemical Communications, 2016, 52, 11438-11441.
9. Xiong Ding, Ying Mu*: Research and Application Progress of Digital Nucleic Acid Amplification Detection Techniques (Review). Chinese Journal of Analytical Chemistry, 2016, 44(4), 512-521.
2012-2015
8. Xiong Ding#, Wenshuai Wu#, Qiangyuan Zhu, Tao Zhang, Wei Jin, Ying Mu*: Mixed-Dye-Based Label-Free and Sensitive Dual Fluorescence for the Product Detection of Nucleic Acid Isothermal Multiple-Self-Matching-Initiated Amplification. Analytical Chemistry, 2015, 87(20), 10306-10314.
7. Xiong Ding#, Kai Nie#, Lei Shi#, Yong Zhang, Li Guan, Dan Zhang, Shunxiang Qi*, Xuejun Ma*: Improved Detection Limit in Rapid Detection of Human Enterovirus 71 and Coxsackievirus A16 by a Novel Reverse Transcription-Isothermal Multiple-Self-Matching-Initiated Amplification Assay. Journal of Clinical Microbiology, 2014, 52(6), 1862-1870.
6. Jianming Luo, Ziqian Xu, Kai Nie, Xiong Ding, Li Guan, Ji Wang, Yuying Xian, Xiyang Wu, Xuejun Ma*: Visual Detection of Norovirus Genogroup II by Reverse Transcription Loop-Mediated Isothermal Amplification with Hydroxynaphthol Blue Dye. Food and Environmental Virology, 2014, 6(3), 196-201.
5. Yalan Zeng, Xiaoguang Zhang, Kai Nie, Xiong Ding, Brian Z Ring, Lanying Xu, Lei Dai, Xiying Li, Wei Ren, Lei Shi*, Xuejun Ma*: Rapid quantitative detection of Human immunodeficiency virus type 1 by a reverse transcription-loop-mediated isothermal amplification assay. Gene, 2014, 541(2), 123-128.
4. Kai Nie#, Xiang Zhao#, Xiong Ding#, Xiaodan Li, Shumei Zou, J.F. Guo, Dayan Wang, Rongbao Gao, Xiyan Li, Weijuan Huang, Yuelong Shu*, Xuejun Ma*: Visual detection of human infection with influenza A (H7N9) virus by subtype-specific reverse transcription loop-mediated isothermal amplification with hydroxynaphthol blue dye. Clinical Microbiology and Infection, 2013, 19(8), E372-375.
3. Xiong Ding, Kai Nie, Ya-Lan Zeng, Ji Wang, Lei Shi, Xue-Jun Ma*: [Establishment of method and modification of colorimetric judgment on HIV-1 virus detection by reverse transcription loop-mediated isothermal amplification] (Article in Chinese). Chinese Journal of Preventive Medicine, 2013, 47(11), 1045-1049. (Non-SCI)
2. Jianyu Su*, Jianping Chen, Lin Li, Bing Li, Lei Shi, Hongmei Zhang, Xiong Ding: Preparation of Natural Borneol/2-Hydroxypropyl-β-cyclodextrin Inclusion Complex and Its Effect on the Absorption of Tetramethylpyrazine Phosphate in Mouse. Chemical and Pharmaceutical Bulletin, 2012, 60(6), 736-742.
1. Xiong Ding, Jianyu Su*, Lei Shi, Lin Li: [Study on composition and antimicrobial activity of the essential oil extracted from fresh leaves of Cinnamomum camphora chvar. Borneol] (Article in Chinese). Science and Technology of Food Industry, 2012, 33(18), 167-171. (Non-SCI)
Advanced Molecular Diagnostics & Devices Lab (AMDDL) 